The Science

The Science

We are leaving the age of supplementation and entering the Age of Activation

Problem #1: Oxidative Stress

One of the main biochemical effects of aging is called oxidative stress and without help, there is no escaping it. Oxidative stress causes your cells to start wearing down. Just like an apple oxidizes after you slice it in half, our cells endure a similar biochemical process and that can lead to hundreds of age related conditions. We’re reversing the process! Our product is proven to reduce oxidative stress 40% on average in just 30 days.

Problem #2: Mitochondrial Decline

The 2nd main biochemical effect of aging. As you age, you start feeling more tired. What you’re experiencing is a natural power drain that happens when your cells don’t produce mitochondria like they used to. Mitochondria are the cellular batteries that power everything, your heart, breathing, and all those ab crunches you may or may not be doing (no judgement here).

Problem #1: Sirtuin Decline

Sirtuins are critical proteins that help keep your cells alie. NAD is a helper enzyme that must be present for sirtuins to exist. As we age, our NAD and sirtuin levels drop by 60%. The NAD Synergizer uses activation to double your sirtuin activity in 24 hours which increases your physical and mental energy and improves cellular health through cellular autophagy (cell detox).

Problem #1:  Oxidative Stress  

One of the main biochemical effects of aging is called oxidative stress and without help, there is no escaping it. Oxidative stress causes your cells to start wearing down. Just like an apple oxidizes after you slice it in half, our cells endure a similar biochemical process and that can lead to hundreds of age related conditions. We’re reversing the process! Our product is proven to reduce oxidative stress 40% on average in just 30 days.

Problem #2: Mitochondiral Decline 

The 2nd main biochemical effect of aging. As you age, you start feeling more tired. What you’re experiencing is a natural power drain that happens when your cells don’t produce mitochondria like they used to. Mitochondria are the cellular batteries that power everything, your heart, breathing, and all those ab crunches you may or may not be doing (no judgement here).

Problem #3:  Sirtuin Decline

Sirtuins are critical proteins that help keep your cells alie. NAD is a helper enzyme that must be present for sirtuins to exist. As we age, our NAD and sirtuin levels drop by 60%. The NAD Synergizer uses activation to double your sirtuin activity in 24 hours which increases your physical and mental energy and improves cellular health through cellular autophagy (cell detox).

 Explaining The Three Theories on Aging
ABC PrimeTime Report on Protandim

Independent
Peer Reviewed Science

There are currently 31 peer reviewed studies on our flagship product, Protandim. It is so unique, universities and research organizations across the world are spending their own money to study the applications & possibilities.

The Protandim Family

LifeVantage is a company using science to approach health differently – we are focused on understanding the major scientific theories of aging and addressing the root causes to be able to take a proactive approach to increasing healthspan.


We specialize in Nutrigenomics – using Nutrients to affect gene expression. Put simply, we use nutrients to tell our bodies how to help themselves.


It all started almost half a century ago, when science proved that our bodies have built in abilities to keep themselves healthy. Two decades ago, a discovery proved that we could tap into those abilities by communicating with our genes through nutrients.

Give Your Cells a Fighting Chance

The discovery that started it all. One of the leading theories of aging is the oxidative stress theory. It is based on the fact that our cells are constantly bombarded by free radicals (we call the subsequent damage “oxidative stress”). Our bodies naturally produce antioxidants to fight oxidative stress, but our antioxidant production begins to decline in our early twenties. Protandim Nrf2 Synergizer was sculpted to activate the Nrf2 pathway, a pathway responsible for antioxidant production. With peer-reviewed studies conducted by the likes of Harvard, Ohio State, the American Journal of Physiology and many more, Protandim Nrf2 Synergizer has been shown to reduce oxidative stress by 40% in just 30 days.*

Take the Power Back

After Protandim Nrf2 Synergizer, we turned our focus to the mitochondrial theory of aging. It is based on the fact that our mitochondria are literally powering everything in our bodies, from our heartbeat to our brain cells and all those ab crunches you may or may not be doing (no judgement here). Unfortunately, our mitochondria decline over time or when stressed. So, we set out to see if we could activate the NRF1 pathway, a pathway responsible for mitochondrial health. After years of research, we launched Protandim® NRF1 Synergizer. Scientifically formulated to help your cells support mitochondrial function.*

Beyond NAD

Recently, scientists have been sharing the immense importance of proteins called sirtuins. Studies are showing sirtuin activity comes with a cascade of health benefits. Including supporting a healthy vascular system, maintaining cholesterol levels already in the healthy range, supporting the body’s healthy inflammatory response, supporting joint health, heightening mental focus, improving mood, motivation, energy, and much more. However sirtuin activity declines as we age (≃60%).


Researchers have discovered that sirtuin activity can be increased through drastic caloric restriction (reducing calories by 40-60%). A typical caloric restriction diet can increase sirtuin activity 94%. Obviously this drastic approach runs the risk of nutrient deficiency and is not recommended without medical supervision.


So, with the knowledge that sirtuin activation requires the molecule NAD, we went to work. Protandim® NAD Synergizer was specifically formulated to target NAD, and has been shown to double sirtuin activity in 24 hours, supporting increased health, focus, energy, mental clarity, and mood. 

Independent Peer Reviewed Science

Our flagship product currently has 26 peer reviewed studies from major universities that have appeared in various scientific and medical journals.

Our technology is patented

We currently hold 6 patents on our technology and 2 international patents. Have you ever heard of another natural product that has been patented?

NIA lifespan study

A recent study by the National Institute for Aging (NIA) discovered that this product showed to extend the median lifespan of male mice by 7%.
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